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Direct Laboratory Services and CellMate Wellness SystemsTM Working for a common goal

January 2002

Contents:
Development of CellMateTM
Panel Subsets: How To Use Them
DLS, CellMate Wellness and Ordering Laboratory Tests Without Your Doctor
The World of Medical Research
Quick Notes

Development of CellMateTM

Recently, there has been some discussion over the development of the CellMateTM Reporting System. Claims have been made that have caused a great deal of confusion. Let us set the record straight using an analogy of the telescope’s discovery.

The telescope allows us to map the universe, discover new planets and galaxies, stars and comets, and the moon. All of these discoveries existed before the creation of the first telescope, they were just brought into view by the new configuration of the lenses.

Beginning in 1985, Mark Schauss started the development of the telescope into the world of medical research and blood tests. In 1996 the system known as CellMateTM was finally brought to market.

As a medical "astronomer", Mr. Schauss began mapping the biochemical universe. Patents were issued with Mark Schauss listed as Lead Inventor. These patents are assigned to Carbon Based Corporation, parent of CellMate Wellness. The Clinical Correlation System, Drug Interactions, Panels/Subsets and the Nutritional Intervention section became the first mapped areas. Other researchers came into the picture as new "astronomers" to assist in the review of medical literature for use in our CellMateTM system.

Today, CellMate Wellness SystemsTM has a world class medical advisory board to review and report new and exciting research through our CellMateTM Reporting System. As always, we will continue to revise and improve our reports to reflect the changing world of nutritional biochemistry.

Panel Subsets: How To Use Them

The Panel/Subset section of the CellMateTM Report is the largest (most number of pages) and potentially the most useful in ascertaining the health status of your patient. The amount of information that can be garnered from this section can be both enlightening and overwhelming at the same time. This article will illustrate how you can more easily make use of this powerful tool.

To better understand the individual panels, we’ll review the history of panels in both the evolution of the CellMateTM report and its use in modern laboratory medicine. Laboratory medicine uses what is known as the Organ Panel/LDRG (Laboratory Diagnosis-Related Group)1 as stand-alone test groups to ascertain the function of a specific area of the patient’s chemistry. Henry and Arras discussed the innovative nature of the use of these panels back in 1970.2 Over the years, these specialized test grouping were used more and more, especially in treating critical-care patient’s. The cardiologist might order a cardiac risk evaluation panel consisting of cholesterol, triglycerides, HDL and Glucose when reviewing a patient. A doctor wanting to review the status of a patient with alcohol related disorders may want to review the patient’s hepatic panel, looking at the results of the AST (sGOT), ALT (sGPT), Alkaline Phosphatase (AP), GGT, Bilirubin, Total Protein, and Albumin. Each specialist has an area they want to see above all others. This method of testing, while effective in ascertaining a specific problem, may miss other potential imbalances and is very cost ineffective.

Use of panel/subsets in the CellMateTM System evolved from the idea that we could use data in a blood test and break out those subsets that allow both the general health care practitioner and the specialist to view specific areas of aberration without the added cost of running multiple tests. Using the CellMateTM Report, you can see how the patient’s overall chemistry is as well as numerous other subgroups.

Recently, we have improved the utility of the panel/subset group by adding short, one or two-line explanations to any panel with a Percent Status Deviation greater than 25%. It is also dependent upon the Percent Status Skew of the panel for any additional meaning the panel may have. These explanations are not meant to be all inclusive, they are another helpful guide to better utilize the CellMateTM Report.
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1 Henry, J.B. Clinical Diagnosis and Management by Laboratory Methods, 18th Ed. W.B. Saunders Company, Philadelphia, PA, 1991.
2 Henry, J.B. and Arras, M.J. Organ Panels: An innovation in health care delivery, Med. Times, 98(2):106, 1970.

Direct Laboratory Services and CellMate Wellness

One hundred and twenty million blood tests are performed in the U.S. annually for diagnostic purposes. One hundred and sixty million people take nutritional supplements daily. Most of them have no idea how much supplementation is healthy for their body.  Wellness screening and nutritional analysis is virtually untouched today. In the future we foresee laboratory testing as the "gold standard" for measuring the necessity and quantity of nutritional supplementation.

In a strategic alliance, Direct Laboratory Services, Inc. (DLS) and CellMate Wellness Systems (CWS) have joined forces to offer the most advanced and comprehensive access to laboratory analysis and interpretation available anywhere in the world. Nowhere else is such a useful and extensive menu of tests obtainable with a single phone call. Even more striking an accomplishment, this alliance not only provides access of these resources to healthcare professionals but also to consumers without the necessity of a physician’s office visit.

We wish to point out that we do not replace the participation of a qualified medical professional for disease treatment. We do, however, assert that a more educated populace with greater access to technical information regarding the biochemistry of good health is entitled to make their own choices regarding the prevention of illness, life-quality improvement or life extension.

One of the inconsistencies plaguing many unhealthy individuals is the laboratory "reference range." Too frequently, ill patients are disappointed by test results that are "within normal limits." The reference ranges on general blood chemistries are sometimes inadequate to identify sufficient abnormalities to suggest a course of therapy or a diagnosis. Some reference ranges are created on mathematically calculated scales instead of biochemical reality. In some cases reference ranges are so broad as to be inconsistent with life.

Interpretation reports from CWS include specific recommendations for nutritional supplementation referenced to peer-reviewed research literature published in internationally recognized medical and scientific journals. You may note the expanded information available as a result of a more realistic correlation of the variances from the median value in the referenced range.

In a cooperative effort, the alliance has and will continue to restructure these reports to make them "consumer-friendly" and reorienting their presentation to address optimal health and wellness rather than disease-orientation.

All of the interpretive information and the supplement recommendations included in the reports are based on an extensive database compiled from the scientific literature. Other reports have been the result of individual interpretations that have not been submitted to peer-review or scientific evaluation. None of the information is arbitrary or anecdotal. Nutritional product recommendations may be generic or they can be brand-specific. Other reports have been the result of individual interpretations that have not been submitted to peer-review or scientific evaluation.

DLS can provide the necessary referrals, service centers, tests, analytical reports and customer support for an even wider range of biochemical evaluations. We contract with associate reference laboratories that meet the highest standards of quality as regulated and monitored by U.S. federal and state government agencies.

Training for professional and consumer groups is being provided to further enable effective use of the report information. Professionals associated with the alliance have represented the leading edge of expertise in nutritional biochemistry for many years. Call for the time and place near you.

Many other analyses are available using advanced technologies to assess wellness such as saliva hormone screens, urinary hormone screens, adrenal profiles, IGF-1, and Somatomedin-C (Human Growth Hormone markers), and intracellular mineral analysis.

Over the last decade, DLS has been given several awards and letters of commendation for the laboratory service programs we provide to the states of Florida, Texas, Mississippi, and Louisiana. We meet the legal requirements for operation in the state of New York, where the most stringent regulations in the U.S. are in effect and we recently received a letter of approval following a review by the New York State Board of Health. We have access to more patient service centers in North America than anyone else. We also have access to a large network of phlebotomists scattered throughout the U.S. We conduct business with over 50 regional reference laboratories throughout the nation that adhere to the highest regulatory standards.

The World Of Medical Research

Using Magnets to Treat Depression

Researchers at the Medical University of South Carolina, led by Mark S. George, reported that a small group (12) of severely depressed or manic depressed adults treated with transcranial magnetic stimulation showed positive results. This study reported in the December 1997 American Journal of Psychiatry may provide clues to drug therapy alternatives, but they do suggest that longer clinical trials should be initiated.

Is ADHD an Evolutionary Trait?

A recent hypothesis about the development of ADHD in humans states that it may be due to our ancestors, dangerous and food-scarce environment. Their theory is that "hair trigger responses would have helped in locating threats and defending against them" in the hostile environment that our hunter-gatherer ancestors would have faced.

These findings were reported in the December 1997 issues of the Journal of the American Academy of Child and Adolescent Psychiatry. In an accompanying comment made by Dr. James F. Leckman of the Yale University School of Medicine, "Rethinking [mental disorders] along developmental and evolutionary lines is clearly a step in the right direction."

Electromagnetic Fields (EMF’s) May Exert Negative Effects on Hormone Levels in Humans

A three-page article in the January 10, 1998 issue of Science News, reiterates growing concerns of the biological effects of EMF’s on the biochemistry of humans. Different forms of cancer such as childhood leukemia and breast cancer have been linked to increased magnetic fields. Other effects are seen in the levels of melatonin, immune system responses, a negative response in the use of drug therapy in the treatment of cancer (especially in the use of tamoxifen), and significantly elevated estrogen levels.

Stronger Evidence Comes Forth on the Price of Second Hand Smoke

Examining 10,914 people in four states, researchers reported in the January 14, 1998 issue of the Journal of the American Medical Association, that people who were in close contact with a smoker for at least 1 hour per week had 20 percent more thickening of their arteries on average than nonsmokers who were not subject to second hand smoke. This would put both those affected by second-hand smoke and ex-smokers at a greater risk for heart disease.

Quick Notes:

If you have any suggestions which would allow us to serve you better, or improve the reports, please let us know!

Mission:

"CellMate Wellness SystemsTM mission is to be the premier
medical research reporting service by continuously researching data
and presenting it in an accurate, easy-to-use and cost effective form."

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